BioClavis is a Glasgow-based R&D and services lab leveraging TempO-Seq® for efficient, scalable transcriptomics in drug discovery, biomarker development and precision medicine.
As a BioSpyder spin-out, BioClavis applies the TempO-Seq targeted-sequencing platform to large cohorts, difficult sample types and high-throughput workflows—helping research teams move from biological questions to actionable molecular insight.
BioClavis combines TempO-Seq chemistry with study design, laboratory services and data support for teams working across discovery and translational research.
Use high-throughput transcriptomics across target discovery, mode-of-action studies, safety, biomarker development and companion diagnostic research.
Explore pharma servicesAccess flexible panels, low-input workflows and scalable profiling for collaborative academic and translational research projects.
Explore academic researchProfile clinically relevant sample types—including FFPE and whole blood—with an approach designed for larger cohorts and biomarker studies.
Explore clinical researchA homepage news layer that surfaces current research activity, platform momentum and team updates without burying visitors in the navigation.
Bring BioSpyder-style platform discovery onto the BioClavis homepage with direct routes to newer assays and capabilities.
Scalable single-cell transcriptomics using split-pool barcoding for high-efficiency cell indexing and downstream analysis.
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Targeted miRNA profiling from low-input sample types, including extracted RNA, cell lysates, FFPE tissue and biofluids.
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A TempO-Seq-derived approach designed around highly specific detector oligos and an additional sample-barcoding layer.
Learn moreA BioClavis-specific applications section that makes the breadth of the platform immediately visible while keeping every route tied to a relevant service page.
Use molecular profiles to support screening, target validation, mode-of-action studies and biomarker programmes.
Explore pharmaApply transcriptomics to low-input and clinically relevant specimens for biomarker development and patient-focused studies.
Explore clinicalProfile pathways, signatures and biological responses using flexible panels and scalable sample throughput.
Explore academicTurn expression count data into interpretable results with exploratory analysis, differential expression and machine-learning support.
Explore bioinformaticsA concise specifications section gives first-time visitors the platform advantages without making them hunt through product pages.
Sample barcoding and short targeted reads make it possible to pool very large numbers of samples per sequencing run.
TempO-Seq supports workflows from crude cell lysates and purified RNA to FFPE tissue, blood and other low-input sample types.
Use focused signatures, surrogate transcriptome panels, custom targets or whole-transcriptome content.
Targeted detector-oligo chemistry avoids several conventional RNA-seq preparation steps and supports automation.
High assay sensitivity supports small input amounts, helping researchers use limited samples more effectively.
BioClavis can support study design, exploratory analysis, differential expression, pathway analysis and classification workflows.
TempO-Seq uses detector oligos to target RNA directly, then ligates, amplifies, barcodes and sequences the resulting products.
Compatible workflows include cell lysates, FFPE material, blood-related inputs and purified RNA.
Target-specific detector oligos bind RNA regions of interest before ligation.
Shared primer sites simplify amplification while sample tags make high-level multiplexing possible.
Short targeted reads support efficient sequencing and streamlined downstream analysis.
Surface evidence of use directly on the homepage, then send researchers to the full BioClavis publications library.
Recent work uses TempO-Seq in transcriptomic biomarker research focused on radiation-induced DNA damage and individual response profiles.
Read on publications pageTempO-Seq data appears in work linking modern toxicogenomic resources with computational and AI-driven approaches.
Read on publications pageSingle-cell transcriptomics work demonstrates TempO-LINC in research investigating cellular stress states for toxicology.
Read on publications pageA homepage FAQ reduces friction for researchers who are deciding whether BioClavis fits a project.
BioClavis describes TempO-Seq workflows for inputs including crude cell lysates, purified RNA, FFPE tissue, whole blood and other low-input sample types. The best preparation depends on the project and assay.
Yes. BioClavis offers off-the-shelf options and can support custom content for genes, transcript variants, mutations and species of interest.
BioClavis supports both kit-based and service-based workflows. Researchers can request quotes for TempO-Seq kits, including miRNA kit options, to run assays in their own laboratory, or work with BioClavis on complete service projects. BioClavis also provides custom panel support and downstream bioinformatics services.
The BioClavis publications page collects key papers and year-by-year references using TempO-Seq, TempO-LINC and related approaches.
Talk to BioClavis about study design, panel selection, sample compatibility, high-throughput transcriptomics and downstream analysis.